Global metabolic profiling employs proton nuclear magnetic resonance (1H NMR) spectroscopy and mass spectrometry (MS). MS has become the key technology in holistic metabolite profiling due to its sensitivity and widespread availability. Generally LCMS-based metabolic profiling in metabolomics aims to offer the widest possible metabolomic coverage. GC-MS untargeted profiling provides superior data quality for the detection of smaller molecules. NMR provides robust data for metabolites of high abundance.

BIOMIC_AUTh team can provide analytical solution in all three analytical modes on LC-HRMS (QTOF), GC-MS and GC-MS/MS and NMR 500 and 600 MHz.

A list of publications on untargeted metabolomics can be found here.

RP UHPLC-TOF MS Lipidomics has emerged as a subgroup of metabolomics dealing with comprehensive lipids analysis. Lipidomics describes the various lipid species present in an organism or sample. Lipidomics involves systems-level identification of pathways and networks, interactions with other biomolecules (e.g proteins) and other moieties in vivo. Application areas include various clinical sciences, nutrition, food biotechnology and others. In particular application in metabolic or cardiovascular diseases, liver function and disease are of high interest.
NMR 500 MHz