30 & 31 October 2008
Teloglion Foundation, Aristotle University of Thessaloniki

Organised with the generous support from AstraZeneca UK and the research Committee of the Aristotle University.

Topics: biomarker discovery, metabonomics/metabolomics, bioinformatics, genomics, proteomics.
Application of technologies such as LC-MS, GC-MS, CE-MS, GC, NMR and advanced statistical analysis.

Target audience: Scientists active in Life sciences, statisticians, analytical chemists, pharmacologists, toxicologists, food control scientists, any other scientists interested to hear about this fascinating multidisciplinary scientific area.

Language: English
Participation: Free

Program & Presentations
30 October
8:15 – 9:15 Registration
9:15 – 9:30 Opening G. Theodoridis
Presenation of the Bioanalysis Network AUTh
9:40 – 10: 50 Introduction to Systems Biology

Moderator G. Theodoridis

M. Arsenakis, Head of Biology School, AUTh
“Introduction to Systems Biology”

A. Tsaftaris, INA, CERTH & AUTh
“From genetics to epigenetics”

S.Tsoka, Kings College UK
“Unraveling the function, evolution and interactions in metabolic pathways through systems biology”

10:50 – 11:05 Coffee Break
11:05 – 13:00 Metabonomics/ Metabolomics: Introduction

Moderator Ian Wilson

Ian D Wilson, AstraZeneca UK
“Systems Biology Introduction: From targeted to non-targeted profiling”
“LC-MS and NMR for metabonomic investigations”

John Shockor, Waters, USA
“Employing Ion-Mobility Mass Spectrometry for Lipidomic Studies”

Discussion

13:00 Lunch Break
14:20 – 16:20 Metabonomics/ Metabolomics:
MS technologies I

Moderator Elwin Verheij

Elwin Verheij, TNO, Zeist ,The Netherlands
“Janus: the two faces of metabolomics”

Steve Fischer, Agilent, CA
“Metabolomics Analysis of Phaseolus vulgaris L. Affect on a Breast Cancer Rat Model with Compound Identification Using an Accurate Mass Retention Time Library”

Discussion

16:20 Coffee Break
16:35 – 17:45 Metabonomics/ Metabolomics:
MS technologies II

Moderator G. Theodoridis

Henri Snijders, Applied Biosystems Europe
“Novel LC/MS workflows in lipidomics”
“Advanced LC/MS Tools to understand Small Molecule Biomarker patterns in targeted and non targeted Metabolomics”

Liz Want, Imperial College London
“LC-MS applications in metabonomics”

Round Table discussion

31 October
9:00 – 11:00 NMR Profiling

Moderator Emmanuel Mikros

Elaine Holmes, Imperial College London
“NMR based metabonomics”

Emmanuel Mikros, Athens University
“NMR profiling studies”

11:00 – 11:15 Coffee Break
11:15 – 13:00 Moderator Maria Klapa Maria Klapa, FORTH, Patras, GR
“Standardisation of GC-MS metabolomic profiling”

Michaela Scigelova, Thermo Fischer
“Overview of MS-based protein quantitation methods”
“Precision -Omics: The Importance of Being Highly resolved and How Accurate. Is Accurate Enough?”

13:00 Lunch Break
14:00 – 16.00 Proteomics

Moderator S. Garbis

S. Garbis, Bioacademy Athens
“The use of quantitative proteomic methods for the simultaneous analysis of potential protein biomarkers and their post-translational variants in breast and prostate cancer research”

Mark McDowall, Waters, USA
“A High Definition Proteomics Strategy – from Global Discovery via Hypothesis Driven Research to Statistically Rigorous Results”

A. Tsarbopoulos, University of Patras, GAIA Research Center
“Role of Mass Spectrometry in the Analysis of Post-Translationally Modified Proteins”

16:00 – 16:30 Closing session Conclusions, Perspectives (Organisers and moderators)
16:30 Coffee, Farewell drink

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